I-Pharmacodynamics flufenicol iyimithi elwa namagciwane esesigabeni se-amidol, i-bacteriosuppressor, futhi isebenza ngokubopha ne-ribosome 50s subunit ukuvimbela ukuhlanganiswa kwamaprotheni ebhaktheriya. Inomsebenzi oqinile we-antibacterial ngokumelene nezinhlobonhlobo zamagciwane e-gram-positive kanye ne-gram-negative. I-Pasteurella hemolyticus, i-pasteurella multocida kanye ne-actinobacillus suis pleuropneumoniae zazizwela kakhulu ku-flufenicol. I-In vitro, umsebenzi we-antimicrobial we-flufenicol ngokumelene namagciwane amaningi uyafana noma unamandla kunalowo we-sulfenicol, futhi amanye amagciwane amelana nama-aminool ngenxa ye-acetylation, njenge-escherichia coli ne-klebsiella pneumoniae, asengazwela ku-flufenicol.
Isetshenziselwa ikakhulukazi izifo ezibangelwa amagciwane ezingulube, inkukhu nezinhlanzi ezibangelwa amagciwane azwelayo, njengezifo zokuphefumula zezinkomo nezingulube ezibangelwa i-pasteurella hemolyticus, i-pasteurella multocida ne-actinobacillus pleuropneumoniae. I-typhoid ne-paratyphoid ebangelwa i-salmonella, ikholera yenkukhu, i-dysentery emhlophe yenkukhu, i-colibacillosis, njll; i-fish pasteurella, i-vibrio, i-staphylococcus aureus, i-hydroomonas, i-enteritis namanye amagciwane abangelwa i-fish bacterial septicemia, i-enteritis, i-erythroderma futhi maduzane.
1. Ama-Macrolides nama-lincosamine anomgomo ofanayo nalo mkhiqizo, ahlanganiswe ne-bacterial ribosome 50s subunit, futhi angaveza imiphumela ephikisanayo uma ehlangene.
2. Ingase ixabanise umsebenzi wokubulala amagciwane wama-penicillin noma ama-aminoglycosides, kodwa akufakazelwanga ezilwaneni.
Ama-antibiotic e-Amidoalcohol, azwela kakhulu ku-Pasteurella hemolyticus, Pasteurella multocida kanye ne-actinobacillus pleuropneumoniae, asetshenziselwa izifo ze-Pasteurella ne-Escherichia coli.
Ngalo mkhiqizo. Ekuphathweni kwangaphakathi: 0.1 ~ 0.15g nge-1kg isisindo somzimba wezingulube nezinkukhu. Izikhathi ezi-2 ngosuku izinsuku ezi-3-5; 50 kuya ku-75mg yezinhlanzi. Sebenzisa kanye ngosuku izinsuku ezi-3 kuya kweziyi-5.
Ukondla okuxubile: Lo mkhiqizo 100g mix 200 ~ 300kg, ukusetshenziswa okuqhubekayo 3 ~ 5 izinsuku.
1. Lo mkhiqizo unomphumela othile we-immunosuppressive uma usetshenziswa ngaphezu komthamo onconyiwe.
2. Inobuthi be-fetus, futhi kufanele isetshenziswe ngokuqapha ngesikhathi sokukhulelwa kanye nemfuyo emunyisayo.
1. Isikhathi sokubekela izinkukhu akufanele sisetshenziswe.
2. Izilwane ezinokuntuleka okukhulu kwamasosha omzimba noma isikhathi sokugoma kufanele zivinjelwe.
3. Izilwane ezinokwehluleka kwezinso kufanele zincishiswe ngendlela efanele noma zelulwe isikhathi sokuphatha.
